The times I've seen this done, it was either painted on or airbrushed.
http://www.cakedivas.com/CakeBook/Cakes/images2/Zebra.jpg
http://www.cakedivas.com/CakeBook/Cakes/images2/Leopard.jpg
I've been thinking of a way to do this without an airbrush or painting. For the leopard print, you could use brown fondant and a leopard spot stencil with black color spray that comes in a can. The zebra could be done the same way with white fondant and a zebra stripe stencil.
http://www.ajunglestore.com/images/animalprintstencil.jpg
You could also use an edible image and put it on the fondant.
Debbie
Hobby lobby used to sell big animal print stamps. You could stamp the pattern on to the fondant with some spray color or by diluting some icing color in vanilla or vodka and dipping the stamp into that mixture.
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