Can I spread ganache over a cake, let it set and then ice over it with buttercream or will it smear?

don't know for sure, but I recall someone doing something like that and it worked ok..... not sure if it were ganache or just melted chocolates, but it gave the cake a "snap" when bit into and it was delicious..... hope you get answers......

I think it would be fine, but I'dd make sure the cake was VERY cold prior to icing it, and thin the buttercream somewhat to make it spread easily withouth "catching" on the chocolate

I needed to know the exact same thing. Thanks for asking this question.

I am making a grand marnier cake with a chocolate ganache filling for my mom's b-day this weekend.

I used the Ganache 1 recipe in the recipes section last week for the cake with the strawberries in my photos and had some left, it is a great recipe.